A bioinformatic service perspective
Key papers:
Weiner 3rd J, Maertzdorf J, Sutherland JS, Duffy FJ, Thompson E, Suliman S, McEwen G, Thiel B, Parida SK, Zyla J, Hanekom WA. Metabolite changes in blood predict the onset of tuberculosis. Nature Communications. 2018 Dec 6;9(1):5208.
Suliman S, Thompson EG, Sutherland J, Weiner 3rd J, Ota MO, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ. Four-gene pan-African blood signature predicts progression to tuberculosis. American Journal of Respiratory and Critical Care Medicine. 2018 May 1;197(9):1198-208.
Duffy FJ, Weiner 3rd J, Hansen S, Tabb DL, Suliman S, Thompson E, Maertzdorf J, Shankar S, Tromp G, Parida S, Dover D. Immunometabolic signatures predict risk of progression to active tuberculosis and disease outcome. Frontiers in Immunology. 2019 Mar 22;10:527.
25% of papers on transcriptomics with a venn diagram fall for this fallacy